VETERINARY PHYSIOLOGY-II                              4 (3-1)

 

Learning outcomes:

 

At the end of the course, students will be able to

1.    Describe basic terminologies related to endocrinology, digestive physiology, lactation and renal physiology. 

2.    Describe relationship of structure to function addressing digestive, renal, lactation and endocrine systems.

3.    Describe pathophysiology of selected disorders of digestive, renal, lactation and endocrine systems.

 

Theory:

Endocrine Physiology: An overview of endocrine system, integration of endocrine and nervous system, Classification and transport of hormones, Hormone-cell interaction and feedback mechanisms, Pituitary Gland, its structure, secretions and function, Thyroid gland, its physiological anatomy, synthesis, release, functions of thyroxin and triiodothyronin, Endocrine pancreas; role of insulin and glucagon in regulation of glucose metabolism, Parathyroid gland: Physiological anatomy; synthesis, release, functions and abnormalities of parathormone and calcitonin. Digestive Physiology: Introduction to gastrointestinal physiology, Feeding behavior, prehension and mastication, enteric nervous system, Physiological mechanism of deglutition, Saliva secretion, composition and regulation, Eructation mechanism, emesis and its control, Ruminant stomach, anatomy and physiology, concept of functional ruminal epithelium, Esophageal groove and concepts of nutrient-by-pass, Microbial ecosystem of digestion in ruminants, Fermentation of carbohydrates, proteins and fats in rumen, Production and absorption of volatile fatty acids, nitrogen in ruminants, Physiologic anatomy of simple stomach, gastric motility, factors affecting gastric motility, Gastric secretion, composition, regulation, factors influencing the gastric secretion, Digestion and absorption of carbohydrates, proteins, fats, Absorption of vitamins end electrolytes, Role of Pancreas and liver indigestion. Clinical cases like ulcer, ruminal acidosis, urea toxicity, diarrhea; Protected nutrients and enzymes, selected antibiotics in feed, probiotic and prebiotics. Lactation Physiology: Functional anatomy of mammary glands, Physiology of mammogenesis, lactogenesis and galactopoesis, Milk synthesis and secretion, Biological functions of milk, its nutritive value, Lactation performance, physiological factors affecting lactation, Mammary biotechnology. Renal Physiology: Anatomy and physiology of Nephron, Urine formation, Glomerular filtration, Physiological control and auto-regulation of Glomerular Filtration Rate, Tubular Reabsorption and processing of Glomerular Filtrate, Mechanism of tubular re-absorption and regulation, Regulation of extra-cellular fluid osmolarity, balance of Sodium and Potassium by Kidney, Renal absorption of bivalent ion. Renal blood flow, renal clearance, filtration fraction, regulation of urine volume and concentration, Act of micturition and its regulation, Introduction to acid–base Physiology, Renal mechanisms for maintaining hydrogen ion concentration in body fluids; Regulation of acid–base balance, Clinical correlations (acidosis, alkalosis). Clinical cases related to Endocrine, Digestive, Lactation and Renal Physiology.

 

Practical:

Demonstration of location of endocrine glands in rats and rabbits, Isolation of rat uterus and effect of oxytocin, Glucose tolerance test, Farm visits for observations on rumination and deglutition; Salivary secretion in ruminants, Tests for saliva of different animals, Motility of ruminant stomach, Rumen fistula/cannulation, Biochemical experiments on bile, Determination of composition of milk, Determination of pH and specific gravity of milk, Determination of total solid in milk, Urinalysis

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